cancer

nheritance of a BRCA1/2 defect predicts such high breast cancer risks that prevention has not been widely studied. Hereditary BRCA1/2 gene mutations can cause cancer by impairing protective responses to some carcinogens. BRCA deficiencies amplify cancer risks from such opportunistic carcinogens. Some hereditary cancers might be preventable by compensating for the BRCA1 or BRCA2 gene mutations.

Dr. Jason Szostek, internist in the Division of General Internal Medicine at Mayo Clinic in Rochester, MN, discusses his article appearing in the February 2012 issue of Mayo Clinic Proceedings describing a phenomena of relief from cyclical vomiting after long term use of marijuana by hot showers. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(11)00026-7/fulltext

Dr. J. Michael Bostwick, Professor of psychiatry at Mayo Clinic in Rochester, MN, discusses his article appearing in the February 2012 issue of Mayo Clinic Proceedings on the potential benefits and current legal limitations for including marijuana in medical research. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(11)00021-8/fulltext

Brief description of GENECAPP procedure

The Wisconsin Center of Excellence in Genomics Science

BACKGROUND INFORMATION: Vesicle trafficking has long been suggested to play mechanistic roles in regulating directed cell migration. Recent evidence demonstrates that specific cell types and modes of migration involve transport of particular cargo through particular pathways. Epithelial wound healing is essential in tissue repair. However, investigations into the mechanisms regulating cell migration have mainly focused upon other models such as fibroblast-derived cells. Roles for vesicle...