cancer

Chronic inflammation and the chemical silencing of tumor-suppressing genes each play roles in development and progression of colorectal cancer. Research published in Nature Medicine led by MD Anderson Provost Raymond DuBois, M.D., Ph.D., connects the two factors by showing the inflammatory small molecule PGE2 silences genes via DNA methylation. http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.2608.html

Find out what motivates about 50 students from The University of Texas at Austin to pedal bicycles for 70 straight days, riding 4,500 miles from Austin to Anchorage, Alaska. Although each has personal reasons, they collectively ride to fight cancer. The Texas 4000 for Cancer organization has given more than $2.5 million for cancer research. In 2011, it endowed a Distinguished Professorship that provides perpetual funding for a researcher at MD Anderson. In October 2011, several of the...

New cancer research for stage 1 lung cancer is being investigated at The University of Texas MD Anderson Cancer Center. It’s led by Jack Roth, M.D., professor in the Department of Thoracic and Cardiovascular Surgery. This clinical trial called STARS (Stereotactic Radiation Therapy Verses Surgery) compares a new type of radiation treatment with a traditional surgery approach. Roth describes this promising new treatment and explains how lung cancer patients may get involved.

Seven years ago, Suzanne Hebert was diagnosed with metastatic breast cancer that spread to her liver and bones. After four rounds of chemotherapy and decreasing response rates, she decided it was time for a change. That change came after advice from a friend, who also had advanced breast cancer, and was enrolled on a clinical trial at MD Anderson. The trial combined two drugs, everolimus, and a hormone therapy called arimidex. A different trial named BOLERO-2, or Breast Cancer Trials of...

Gabriel Hortobagyi, M.D., professor and chair of MD Anderson's Department of Breast Medical Oncology, discusses the BOLERO-2 trial and the implications for patients.

Lorenzo Cohen, Ph.D., discusses a new clinical trial that will test the effects of lifestyle changes on cancer recurrence. Breast cancer patients in the study will receive coaching on nutrition, exercise, stress reduction and strengthening their social connections.