Vanderbilt University researchers say they're working to unleash an insect repellent on mosquitoes that's more powerful than DEET. The discovery could one day be effective in reducing the spread of mosquito-borne diseases, such as malaria. It's based on a mosquito's sense of smell. With early support from the National Science Foundation, Vanderbilt University biologist Laurence Zwiebel researched which mosquito genes are linked to odor reception. Since then, he's discovered a separate odor...

Background: In sub-Saharan Africa, ~40% of children <5 y old are stunted, with levels that have remained largely unchanged over the past 2 decades. Although the complex determinants of undernutrition are well recognized, few studies have evaluated strategies that combine nutrition-specific, health-based approaches with food system– and livelihood-based interventions. Objective: We examined changes in childhood stunting and its determinants after 3 y of exposure to an integrated,...

Jean-Claude Bradley presents a 15 minute summary of current research in his lab on September 29, 2011 at the Drexel University Department of Chemistry Faculty Mini-Symposium. The main project discussed is the Open Melting Point Collection done in collaboration with Andrew Lang and Antony Williams. Work by Evan Curtin is also shown, demonstrating the application of melting point and solubility in reaction design.

Cette présentation couvrira des méthodes et des outils utilisés pour rassembler, enregistrer et disséminer l'information chimique utilisant la Science par Cahier de Laboratoire Ouvert, la pratique de rendre un cahier de laboratoire et tous données brutes associées disponibles publiquement aussitôt que possible. Des mesures de solubilité et les réactions de chimie organique sont manipulées de cette façon. L'enregistrement des données de laboratoire est manipulé principalement...

Jean-Claude Bradley presents "Accelerating Discovery by Sharing: a case for Open Notebook Science" on May 1, 2011 at the National Breast Cancer Coalition Annual Advocacy Conference in Arlington, VA. First a few examples are provided which show how a lack of transparency in science can retard progress by creating ambiguity. Demonstrations of the use of Open Notebook Science in malaria research, solubility and other chemistry related applications then follow. Examples of web services...

In episode 44 of MicrobeWorld Video filmed at the American Association for the Advancement of Science Meeting in Washington, D.C., Dr. Stan Maloy talks with Beatrice Hahn, Professor of Medicine and Microbiology at the University of Alabama at Birmingham, about her work on the origins of HIV and Malaria, and how these diseases may have spread to humans.

In this video, high school students and their teachers participate in a simple activity to demonstrate the interaction between the var antigens malaria parasites display and the patient's immune system.

The main objective of the AntiMal Integrated Project is to generate novel antimalarial drugs with potential for use in humans, specifically to progress candidate molecules to the “first time into humansâ€? stage of drug development. To achieve this goal, leading groups of malaria researchers from Europe and Africa with expertise in malaria biology, chemotherapy and drug development have come together to exploit new scientific and political opportunities to secure the development of a...

Dana Vanderwall, Associate Director of Cheminformatics at Bristol-Myers Squibb, presented at Drexel University for Jean-Claude Bradley's Chemical Information Retrieval class on December 2, 2010. The first part covers "Cheminformatics & The evolving relationship between data in the public domain & pharma" and includes a general discussion of modern drug discovery and the details of a malaria dataset recently released from the pharmaceutical industry to the public. The second part...

Jean-Claude Bradley presents on "The implications of Open Notebook Science and other new forms of scientific communication for Nanoinformatics" at the Nanoinformatics 2010 conference on November 3, 2010. The presentation first covers the use of the laboratory knowledge management system SMIRP for nanotechnology applications during the period of 1999-2001 at Drexel University. The exporting of single experiments from SMIRP and publication to the Chemistry Preprint Archive is then described...