he administration of anti-trypanosome nitroderivatives curtails Trypanosoma cruzi infection in Chagas disease patients, but does not prevent destructive lesions in the heart. This observation suggests that an effective treatment for the disease requires understanding its pathogenesis. To understand the origin of clinical manifestations of the heart disease we used a chicken model system in which infection can be initiated in the egg, but parasite persistence is precluded. T. cruzi...
Authors: Teixeira Antonio rl, Gomes Clever, Nitz Nadjar, Alessandro sousa, Alves Roseneide, Sousa Alessandro, Cambraia Maria carolina, Cordeiro Ciro, Bernal Francisco m, Rosa Ana cassia, Hejnar Jiri, Leonardecz Eduardo, Hecht Mariana m