environments

George Church (Harvard University) keynote talk for DOE Joint Genome Institute (JGI) '09 Church elaborates on the future direction and development of genomic sequensing and reducing the cost of genomic research, while increasing the efficiency and possibilities, inclusive of developing multivirus resistance genomes. User Meeting on March 26, 2009, with introduction by Len Pennacchio (JGI). George Church (Harvard University) keynote talk for DOE JGI '09 User Meeting on March 26, 2009, with...

The human microbiome is a complex system of many microbial communities inhabiting a diversity of environmental niches throughout the human body. With at least an order of magnitude more cells and even greater diversity of genetic potential these microbial communities continually interact with the human host cells in complex but controlled manner that lead to normal human health. Our knowledge of the structure and function of these communities and the interactions with the human host is...

The Gazetteer (Gaz) is a community-based project of the EnvO Consortium for describing instances of organism environments and biological samples supporting consistent annotation of locations and environments. The Gazetteer describes places and place names, and the relations between them. The Gaz, with 130,000 plus terms (over 50 % of terms defined) and relations, is being utilizing in scientific investigations such as applying Gaz terms to organisms based on free-text from the Encyclopedia of...

Sequencing the expressed genetic information of an ecosystem (metatranscriptome) can provide information about the response of organisms to varying environ mental conditions. Until recently, metatranscriptomics has been limited to microarray technology and random cloning methodologies. The application of high-throughput sequencing technology is now enabling access to both known and previously unknown transcripts in natural com munities. We present a study of a complex marine meta...